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Face & Aesthetics · Ms Anna De Leo

Skin Rejuvenation Harley Street · London

Medical-grade peels, exfoliation and skin boosters to refine texture, soften fine lines and acne scarring, and bring back healthy, even radiance.

7 min read 64 Harley Street, W1G Female Plastic Surgeon · GMC registered
Anaesthetic None, topical or local
Treatment time 20–60 minutes
Hospital stay None, clinic treatment
Back to work Same day to 1 week
Final result After a course, 1–3 months

Typical ranges only — your personal plan is confirmed at consultation.

Skin rejuvenation focuses on the surface and quality of the skin itself: its texture, tone, clarity, hydration and fine lines. At her Harley Street practice in London, female plastic surgeon Ms Anna De Leo offers a carefully selected range of treatments, including medical chemical peels, dermabrasion and microdermabrasion, and hyaluronic acid skin boosters, to improve fine wrinkles, acne scarring, sun damage and dull, uneven skin.

Unlike a facelift or fillers, which address structure and volume, skin rejuvenation works on the outermost layers, encouraging the skin to renew itself and produce fresh collagen. Results are gradual and natural rather than dramatic, and no treatment can erase every line or scar completely; but a well-chosen course can make a visible, lasting difference to how healthy your skin looks and feels. As a plastic surgeon with more than twenty years of experience, Ms De Leo assesses your skin medically before recommending anything, so that each treatment is suited to your skin type, colour and goals.

01What Is Skin Rejuvenation?

Skin rejuvenation is an umbrella term for treatments that improve the skin's surface by controlled exfoliation, stimulation of collagen and restoration of hydration. With time, sun exposure, pollution, smoking, hormonal changes and conditions such as acne, the skin accumulates damage: cell turnover slows, collagen and elastin decline, pigment becomes uneven, pores look larger and fine lines and scars become more noticeable.

By removing the outermost layers in a precise and controlled way, or by delivering hydrating molecules into the dermis, these treatments prompt the skin's natural repair processes. New, smoother cells replace older, damaged ones, and fibroblasts are stimulated to produce new collagen over the following weeks. The result is a firmer, smoother, brighter complexion.

It is worth being clear about what skin rejuvenation is not. It does not lift sagging tissues or restore lost facial volume. Those concerns are addressed by a facelift or dermal fillers, while a holistic, combined plan is covered under facial rejuvenation.

02Who Can Benefit from Skin Rejuvenation?

Skin rejuvenation treatments can help adults of almost any age who are concerned about:

  • Fine lines and wrinkles, including those around the mouth and eyes
  • Acne scarring, from shallow rolling scars to textural irregularity
  • Sun damage, uneven pigmentation and age spots
  • Dull, dehydrated or rough skin and enlarged pores
  • Mild active acne, under medical supervision

Careful selection is essential. Deeper peels and resurfacing carry a greater risk of pigment change in darker skin types, and treatment may need to be adapted or avoided. Exfoliating treatments are postponed if you have active cold sores, infection or eczema in the area, if you have recently used isotretinoin, or during pregnancy for certain products. Ms De Leo will review your medical history and skin type to make sure that any recommendation is appropriate and safe.

03Your Skin Consultation on Harley Street

Your consultation takes place at 64 Harley Street in Marylebone. Ms Anna De Leo will ask about your skin history, current skincare, medications, sun exposure and any previous treatments, and will examine your skin closely, often under good lighting with photographs, to understand texture, pigment, scarring and skin type.

She will then build a personalised plan, which may combine in-clinic treatments with a home skincare routine, sun protection and lifestyle measures. Expectations are discussed openly: you will know how many sessions are likely to be needed, what downtime to expect and how much improvement is realistic for your particular concern.

The cost of a skin rejuvenation plan depends on the treatments chosen, the depth and number of sessions, the areas treated and whether home care products and maintenance are included. Everything is explained in a clear written plan before you commit, and you are always welcome to take time to consider it.

04Skin Rejuvenation Treatments We Offer

Chemical peels

Medical peels use carefully selected acids, such as glycolic, lactic, salicylic, mandelic or trichloroacetic acid, to exfoliate the skin to a controlled depth. Superficial peels brighten and smooth with little downtime and are usually given as a course. Medium-depth peels treat more established fine lines, pigmentation and shallow acne scarring, with several days of peeling.

Dermabrasion and microdermabrasion

Microdermabrasion gently polishes away the outermost layer of dead cells for smoother, fresher skin with no downtime. Dermabrasion is a deeper, more intensive form of exfoliation that removes the superficial layer of the skin in a controlled way, giving a firmer, smoother surface. It can soften wrinkles around the mouth and acne scarring, although no treatment can remove them completely.

Hyaluronic acid skin boosters

Very fine injections of soft hyaluronic acid are placed into the dermis to biorevitalise the skin, improving hydration, elasticity and glow and stimulating new collagen. Results are temporary, so a course followed by maintenance treatments is usually recommended.

Targeted treatment for acne scars

Acne scars come in different forms, and treatment is matched to the type: resurfacing for textural scars, small-volume filler for rolling scars and, for selected deeper scars, minor surgical techniques such as subcision or punch excision as part of a staged plan.

Healthy skin is the foundation of every beautiful face; refining its quality often achieves more than any change in shape.

ADLSynergy · Harley Street

05Recovery and Aftercare

Most skin rejuvenation treatments involve little or no downtime, which is one of their great advantages:

  • Superficial peels and microdermabrasion: mild redness for a few hours to a day; return to work the same day.
  • Medium-depth peels and dermabrasion: redness, tightness and peeling for around five to ten days, with fresh, pink skin settling over the following weeks.
  • Skin boosters: small bumps at injection points that settle within a day or two, with occasional bruising.

Rigorous sun protection with a broad-spectrum SPF is essential after any exfoliating treatment, and you will be advised on gentle cleansing, moisturising and when to restart active products such as retinoids. Our team in London can support recovery with nutrition guidance and red light therapy where appropriate, as part of the ADLSynergy focus on skin health and longevity.

06Risks and Realistic Results

Although non-surgical, skin rejuvenation treatments are medical procedures with potential side effects:

  • Redness, swelling, tightness, peeling or temporary sensitivity
  • Temporary darkening or lightening of the skin, particularly in darker skin types
  • Reactivation of cold sores, which can be reduced with preventive medication
  • Infection, or, with deeper treatments, rarely, scarring
  • For skin boosters: bruising, small lumps and, rarely, sensitivity reactions

Before and after results from skin rejuvenation can be significant, but they build gradually and vary between individuals. Improvements are reductions rather than complete removal of lines and scars, and maintenance is needed because the skin continues to age. Consistent sun protection and a good home routine help preserve your result for longer.

07Building a Long-Term Skin Rejuvenation Plan in London

The most rewarding skin rejuvenation results rarely come from a single appointment. Skin renews itself over a cycle of roughly four to six weeks, and collagen remodelling continues for months, so the best outcomes come from a considered programme rather than isolated treatments. A typical plan on Harley Street might begin with skin preparation at home for several weeks, followed by a course of superficial peels or skin boosters, with deeper resurfacing reserved for specific concerns such as acne scarring.

Your plan also reflects the seasons. Deeper peels and resurfacing are often best scheduled in the autumn and winter, when the sun in London is weaker and it is easier to protect healing skin. Maintenance sessions every few months then help to preserve your progress.

Above all, the plan is built around you: your skin type, your lifestyle, how much downtime you can accommodate and what matters most to you. Regular reviews allow Ms Anna De Leo to adjust treatments as your skin responds, so that improvement stays steady, safe and natural.

08Why Choose Ms Anna De Leo on Harley Street

Ms Anna De Leo is a GMC-registered Plastic, Reconstructive and Aesthetic Surgery Consultant and Fellow of the European Board of Plastic, Reconstructive and Aesthetic Surgery, with extensive experience in skin surgery, scar management and facial reconstruction. Her understanding of how skin heals informs every recommendation, whether it is a gentle peel or a carefully staged plan for acne scarring.

As a female plastic surgeon, she brings a meticulous, caring approach to skin, valuing a natural, healthy glow over a heavily treated look. For deeper concerns, she can combine skin treatments with surgical or injectable options in a single, coherent plan.

To discuss skin rejuvenation at our Harley Street practice in London, please get in touch.

Ms Anna De Leo, female plastic surgeon on Harley Street, London
Your Surgeon

Ms Anna De Leo

Plastic, Reconstructive & Aesthetic Surgery Consultant on Harley Street, London. Over 20 years of experience across cosmetic and reconstructive surgery, trained in leading NHS and international centres — from Chelsea and Westminster, the Royal Free and Oxford University Hospitals to Barcelona, Helsinki and Belo Horizonte.

  • GMC Registered
  • FEBOPRAS
  • BAPRAS Member
  • European Diploma in Hand Surgery
  • Master's in Reconstructive Microsurgery
Skin Rejuvenation · Harley Street

Frequently Asked Questions

What is the difference between skin rejuvenation and facial rejuvenation?
Skin rejuvenation focuses on the surface and quality of the skin: texture, fine lines, pigmentation, acne scarring and hydration, using peels, exfoliation and skin boosters. Facial rejuvenation is a broader, combined plan that also addresses volume loss and sagging, potentially including fat grafting, fillers or a lift alongside skin treatments and lifestyle support.
How many chemical peel sessions will I need?
Superficial peels are usually given as a course of around three to six sessions, spaced two to four weeks apart, followed by occasional maintenance. Medium-depth peels are usually carried out as a single treatment or repeated after several months. The right number depends on your skin and your concerns and will be planned at your consultation.
Can acne scars be removed completely?
Acne scars can often be improved significantly, but rarely removed entirely. Different types of scar respond to different treatments, so a combined, staged plan, which might include resurfacing, peels, fillers and minor surgical techniques, usually gives the best results. Ms De Leo will be honest about the degree of improvement you can expect.
Is there downtime after skin rejuvenation?
It depends on the treatment. Superficial peels, microdermabrasion and skin boosters typically involve little or no downtime, and most people return to work the same day. Medium-depth peels and dermabrasion involve around five to ten days of redness and peeling, so many people plan them around a quieter week.
Are skin rejuvenation treatments suitable for darker skin?
Many treatments can be used safely in darker skin, but the risk of temporary pigment change is higher, particularly with deeper peels and resurfacing. Treatments may need to be adapted, skin may need preparation beforehand, and some options are best avoided. A careful medical assessment ensures your plan is suitable for your skin type.
How can I make my results last?
Daily broad-spectrum sun protection is the single most important step, together with a consistent skincare routine, not smoking, good sleep and a nutrient-rich diet. Maintenance treatments every few months help to sustain improvements, because the skin continues to age. Our team can advise on a long-term plan for skin health.
Quick Answers · Harley Street London Surgery

Skin Rejuvenation on Harley Street:
Visiting & Booking

Everything you need to know about having skin rejuvenation with Ms Anna De Leo at 64 Harley Street, London — opening hours, booking and getting here.

Where can I have skin rejuvenation in London?
You can have skin rejuvenation with Ms Anna De Leo at ADLSynergy, 64 Harley Street, Marylebone, London W1G 7HB. The practice sits on Harley Street, the historic centre of British private medicine, and offers private consultations every day, Monday to Sunday, from 9:00am to 6:30pm, by appointment.
Who performs skin rejuvenation at the Harley Street practice?
Every skin rejuvenation consultation and procedure is led personally by Ms Anna De Leo, a GMC-registered Plastic, Reconstructive & Aesthetic Surgery Consultant, Fellow of the European Board of Plastic, Reconstructive and Aesthetic Surgery (FEBOPRAS) and member of BAPRAS. She is a female surgeon with more than 20 years of experience, seeing patients at 64 Harley Street, London.
What are the opening hours of the Harley Street clinic for skin rejuvenation consultations?
The ADLSynergy practice at 64 Harley Street is open every day, Monday to Sunday, from 9:00am to 6:30pm. All skin rejuvenation consultations are by appointment, so please book ahead by phone, WhatsApp, email or the online contact form.
How do I book a skin rejuvenation consultation on Harley Street?
Call +44 (0) 7732 475 751, message the team on WhatsApp, email info@adlsynergy.co.uk or use the contact form at adlsynergy.co.uk/contact.html. A member of the team will reply within 24 hours to arrange your skin rejuvenation consultation with Ms Anna De Leo at 64 Harley Street, London W1G 7HB.
Can I book a skin rejuvenation appointment at the weekend in London?
Yes. Unlike many Harley Street clinics, the ADLSynergy practice is open seven days a week, including Saturday and Sunday, from 9:00am to 6:30pm. Weekend skin rejuvenation consultations are by appointment — call +44 (0) 7732 475 751 or send a WhatsApp message to check availability.
Do I need a GP referral for skin rejuvenation on Harley Street?
No referral is needed to book a private skin rejuvenation consultation with Ms Anna De Leo at 64 Harley Street. If you plan to claim through private medical insurance, check with your insurer, as some ask for a GP referral first. Bringing a GP letter or any previous reports is always helpful.
What anaesthetic is used for skin rejuvenation on Harley Street?
Typical anaesthetic for skin rejuvenation: None, topical or local. Ms Anna De Leo confirms the safest option for you at your consultation at 64 Harley Street, London, after reviewing your health and goals.
How soon can I return to work after skin rejuvenation?
Typical time back to desk-based work after skin rejuvenation: Same day to 1 week. Everyone heals differently, so Ms Anna De Leo gives you a personalised recovery timeline at your consultation at 64 Harley Street, London, and follows you up throughout.
What should I bring to my skin rejuvenation consultation in London?
Please bring photo ID, a list of your medications and allergies, details of any previous surgery, relevant scans or reports, and the questions you would like to ask. Ms Anna De Leo will take a full history at her Harley Street practice before recommending any skin rejuvenation plan.
How do I get to the skin rejuvenation clinic at 64 Harley Street?
64 Harley Street is a short walk from Regent's Park, Oxford Circus, Bond Street, Great Portland Street and Baker Street Underground stations, and from Marylebone mainline station. Directions and a map are on the Harley Street practice page at adlsynergy.co.uk.
Why choose Harley Street for skin rejuvenation?
Harley Street has been the centre of British consultative medicine since the 19th century, with specialist doctors concentrated in one Marylebone address. At 64 Harley Street, Ms Anna De Leo combines that tradition with a personalised, female-led approach to skin rejuvenation and coordinated recovery support.
Does ADLSynergy offer recovery support after skin rejuvenation?
Yes. After skin rejuvenation, the ADLSynergy team on Harley Street offers scar therapy, lymphatic care, oxygen and red light therapy, nutrition and breathwork support, all coordinated with Ms Anna De Leo's surgical plan to help you recover well.
Is my skin rejuvenation consultation confidential?
Completely. Consultations take place privately at 64 Harley Street in a calm, discreet setting, and your personal and medical information is handled confidentially in line with UK GDPR. You can also ask initial questions about skin rejuvenation by WhatsApp before booking.
Can I see Ms Anna De Leo about skin rejuvenation outside London?
Ms Anna De Leo's main practice is at 64 Harley Street, London W1G 7HB, open every day, Monday to Sunday, from 9:00am to 6:30pm. She also sees patients in Rome and Palermo, Italy, by appointment — contact the team on +44 (0) 7732 475 751 to arrange a skin rejuvenation consultation.
How long should I wait between my skin rejuvenation consultation and surgery?
In line with GMC guidance, there is a cooling-off period of at least two weeks between your consultation and any cosmetic procedure. Ms Anna De Leo encourages a second consultation at 64 Harley Street so you can decide on skin rejuvenation without any pressure.
64 Harley Street · London W1G

Discuss Skin Rejuvenation
with Ms Anna De Leo

Every transformation starts with a conversation. Book a private consultation at our Harley Street practice — open every day, by appointment.

This guide is for general information and does not replace a personal medical consultation. All surgery carries risks; results vary from person to person.

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