IMPROVE PERFORMANCE IN LIFE LONGEVITY RESHAPES YOU ADLSYNERGY · HARLEY STREET LONDON PLASTIC · RECONSTRUCTIVE · AESTHETIC SURGERY POST-PREGNANCY TRANSFORMATION RECOVERY SCIENCE · NUTRITION · BREATHWORK IMPROVE PERFORMANCE IN LIFE LONGEVITY RESHAPES YOU ADLSYNERGY · HARLEY STREET LONDON PLASTIC · RECONSTRUCTIVE · AESTHETIC SURGERY POST-PREGNANCY TRANSFORMATION RECOVERY SCIENCE · NUTRITION · BREATHWORK
Face & Aesthetics · Ms Anna De Leo

Dermal Fillers Harley Street · London

Subtle, doctor-led hyaluronic acid fillers to restore lost volume and soften lines, planned by a plastic surgeon with a deep knowledge of facial anatomy.

6 min read 64 Harley Street, W1G Female Plastic Surgeon · GMC registered
Anaesthetic Topical or local
Treatment time 30–60 minutes
Hospital stay None, clinic treatment
Back to work Usually the same or next day
Results last 6–18 months, product dependent

Typical ranges only — your personal plan is confirmed at consultation.

Dermal fillers are gel-like injectable treatments used to restore lost volume, soften lines and folds, and gently enhance features such as the lips, cheeks and jawline. At her Harley Street practice in London, female plastic surgeon Ms Anna De Leo offers dermal fillers as a medical treatment, carried out by a consultant plastic surgeon rather than as a quick beauty service, with an emphasis on subtle, balanced results that look like a well-rested version of you.

Fillers can look deceptively simple, but they are not. In the UK, dermal fillers are not licensed as medicines, and there is currently no legal requirement for the person injecting them to be medically qualified. That makes your choice of practitioner one of the most important decisions you will make. A surgeon who understands the layers, blood vessels and ageing patterns of the face is best placed to choose the right product, place it safely and recognise and treat any complication promptly.

01What Are Dermal Fillers?

Most modern dermal fillers are made from hyaluronic acid, a sugar molecule found naturally in the skin, where it binds water and helps to keep tissues hydrated, supple and plump. With age, the body's own hyaluronic acid and collagen decline, fat compartments shrink and shift, and bone gradually remodels. The result is hollowing in the temples and under the eyes, flattening of the cheeks, deepening folds around the nose and mouth, and thinner lips.

Hyaluronic acid fillers come in a range of densities. Firmer gels are placed deeply to restore structure in the cheeks, chin or jawline; softer gels are used in the lips or to smooth finer lines; and very fluid ‘skin booster’ products hydrate the skin and support its quality. Over time, the body gradually breaks the product down, which is why results are temporary, typically lasting from around six months to eighteen months or more, depending on the product and the area treated.

A key advantage of hyaluronic acid is that it can be dissolved. An enzyme called hyaluronidase, a prescription-only medicine, can break down the filler if a result needs adjusting or, much more importantly, if a complication occurs. Because of this reversibility and safety profile, our practice favours hyaluronic acid. Permanent and semi-permanent fillers are generally avoided in modern UK practice, as complications such as late lumps and inflammation are harder to treat.

02Who Are Fillers Suitable For?

Dermal fillers can help people from their late twenties onwards who wish to address specific concerns without surgery, including:

  • Volume loss in the cheeks, temples or mid-face
  • Nasolabial folds and marionette lines around the mouth
  • Thin or asymmetric lips, or fine lines around the lips
  • A recessed chin or a softened jawline
  • Hollows beneath the eyes (tear troughs), in carefully selected patients
  • Acne scarring or skin that has lost hydration and glow

Fillers are not suitable during pregnancy or breastfeeding, in the presence of active skin infection near the treatment area, or for some people with certain autoimmune conditions or a history of severe allergies. In England, it has been illegal since October 2021 to give dermal fillers to anyone under the age of 18 for cosmetic purposes, and we do not treat under-18s.

Fillers also have limits. They cannot lift heavy, loose skin, and overfilling a face to compensate for sagging tends to look unnatural. If laxity is your main concern, a facelift or a combined facial rejuvenation plan may be more appropriate.

03Your Fillers Consultation on Harley Street

Every treatment begins with a proper medical consultation at 64 Harley Street, Marylebone, in central London. Ms Anna De Leo will review your medical history, medications and any previous injectable treatments, and assess your face at rest and in movement. She considers the face as a whole, looking at proportion, symmetry and how volume has changed over time, rather than simply filling individual lines.

You will discuss the areas that concern you, which products are appropriate, how much is likely to be needed, how long results may last and the possible side effects. If fillers are not the right answer for you, she will say so. Responsible practice also means allowing you time to reflect: you will never be pressured to proceed on the day.

The factors that influence the cost of filler treatment include the areas treated, the type and volume of product, and whether a review appointment or follow-up treatments are planned. These are explained clearly in a personalised plan.

04How Dermal Filler Treatment Is Performed

After cleansing the skin, a topical anaesthetic cream may be applied, and many products also contain a small amount of local anaesthetic to keep treatment comfortable. For the lips, a dental-style nerve block may be offered. Ms De Leo then injects the filler precisely, using either a very fine needle or a blunt-tipped cannula, which can reduce bruising and lower the risk of entering a blood vessel in some areas.

  • Cheeks and mid-face: structural support that lifts and softens the folds below.
  • Lips: gentle definition of the border and natural hydration of the body of the lip, respecting your natural proportions. See also chin and lip reshaping.
  • Chin and jawline: improved projection and a cleaner profile.
  • Lines and folds: softening, rather than erasing, to keep expression natural.

Treatment usually takes thirty to sixty minutes. A cautious, staged approach is often best: it is always possible to add more at a review appointment, but a subtle start keeps results natural.

Good filler work is invisible: people notice that you look well, never that you have had something done.

ADLSynergy · Harley Street

05Recovery and Aftercare After Fillers

Most people return to normal activities the same day or the next. Mild swelling, redness, tenderness and small bruises at injection sites are common, particularly in the lips, and usually settle within a few days to a week. Lips can look fuller for the first forty-eight hours before settling.

  • Avoid make-up on the treated area for the rest of the day
  • Avoid strenuous exercise, saunas, steam rooms and alcohol for around 24–48 hours
  • Do not massage the area unless advised
  • Avoid dental work and facial treatments for two weeks if possible
  • Contact the clinic immediately if you notice severe or increasing pain, skin colour change, blanching or any change in vision

A review appointment around two weeks after treatment allows the result to be assessed once swelling has settled. At ADLSynergy on Harley Street in London, fillers can form part of a wider plan to support skin health, including nutrition guidance and treatments to improve skin quality, linked to our longevity approach.

06Dermal Filler Risks and Safety

Dermal fillers are non-surgical, but they are a medical procedure with genuine risks. These include:

  • Swelling, bruising, redness and tenderness, usually short-lived
  • Lumps, unevenness or asymmetry, which may settle or be corrected
  • Infection, or delayed inflammatory reactions weeks or months later
  • A bluish discolouration if filler is placed too superficially
  • Allergic or sensitivity reactions, which are rare with hyaluronic acid
  • Vascular occlusion: if filler blocks a blood vessel, it can damage the skin and, very rarely, cause loss of vision. This is a medical emergency requiring immediate treatment with hyaluronidase.

Rapid recognition and treatment of complications are why it matters so much to choose a qualified doctor who holds hyaluronidase on site and knows how to use it. When looking at filler before and after photographs, remember that results vary and that the product is gradually absorbed, so maintenance treatments are needed to sustain the effect.

07Why Choose Ms Anna De Leo for Fillers on Harley Street

Ms Anna De Leo is a GMC-registered Plastic, Reconstructive and Aesthetic Surgery Consultant and Fellow of the European Board of Plastic, Reconstructive and Aesthetic Surgery, with more than twenty years of experience in facial surgery and reconstruction. That surgical knowledge of facial anatomy, including the course of blood vessels and nerves, underpins a safe, considered approach to dermal fillers.

As a female plastic surgeon, she favours restraint and harmony: enhancing what is already there, rather than chasing trends. Patients looking for the best filler doctor in London often value precisely this blend of medical expertise and an eye for natural beauty.

To discuss dermal fillers in a relaxed, clinical setting, please book a consultation at our Harley Street practice in London.

Ms Anna De Leo, female plastic surgeon on Harley Street, London
Your Surgeon

Ms Anna De Leo

Plastic, Reconstructive & Aesthetic Surgery Consultant on Harley Street, London. Over 20 years of experience across cosmetic and reconstructive surgery, trained in leading NHS and international centres — from Chelsea and Westminster, the Royal Free and Oxford University Hospitals to Barcelona, Helsinki and Belo Horizonte.

  • GMC Registered
  • FEBOPRAS
  • BAPRAS Member
  • European Diploma in Hand Surgery
  • Master's in Reconstructive Microsurgery
Dermal Fillers · Harley Street

Frequently Asked Questions

How long do dermal fillers last?
Hyaluronic acid fillers usually last between six and eighteen months, depending on the product, the area treated and your individual metabolism. Areas that move a lot, such as the lips, tend to break the filler down more quickly than deeper areas such as the cheeks or chin. Maintenance treatments can be planned to sustain the result if you wish.
Can dermal fillers be reversed?
Hyaluronic acid fillers can be dissolved with an enzyme called hyaluronidase, which is a prescription-only medicine. This can be used to correct an unwanted result and, more importantly, to treat a complication such as a blocked blood vessel. This reversibility is one reason our practice favours hyaluronic acid over permanent fillers.
Are dermal fillers regulated in the UK?
Dermal fillers are regulated as medical devices rather than licensed medicines, and at present there is no legal requirement for the person injecting them to be medically qualified, although the government has announced plans for licensing. Since October 2021 it has been illegal in England to give cosmetic fillers to under-18s. Choosing a qualified, regulated doctor is the best protection.
Do fillers hurt?
Most people find filler treatment very tolerable. A numbing cream is usually applied beforehand, many products contain local anaesthetic, and for the lips a dental-style nerve block can be offered. You may feel some pressure or brief stinging during injection, and the area may be tender for a day or two afterwards.
Will I look overdone after fillers?
Not if treatment is planned carefully. Ms De Leo takes a conservative, staged approach, using the minimum product needed to restore balance and reviewing the result after two weeks. The aim is that you look refreshed and well, with natural movement and expression, rather than obviously treated.
What is the difference between fillers and anti-wrinkle injections?
Dermal fillers add volume and structure, restoring areas that have hollowed or flattened and softening static folds. Anti-wrinkle injections are a prescription medicine that relaxes specific muscles to soften lines caused by movement, such as frown lines. The two treat different causes of ageing and are sometimes used together.
Quick Answers · Harley Street London Surgery

Dermal Fillers on Harley Street:
Visiting & Booking

Everything you need to know about having dermal fillers with Ms Anna De Leo at 64 Harley Street, London — opening hours, booking and getting here.

Where can I have dermal fillers in London?
You can have dermal fillers with Ms Anna De Leo at ADLSynergy, 64 Harley Street, Marylebone, London W1G 7HB. The practice sits on Harley Street, the historic centre of British private medicine, and offers private consultations every day, Monday to Sunday, from 9:00am to 6:30pm, by appointment.
Who performs dermal fillers at the Harley Street practice?
Every dermal fillers consultation and procedure is led personally by Ms Anna De Leo, a GMC-registered Plastic, Reconstructive & Aesthetic Surgery Consultant, Fellow of the European Board of Plastic, Reconstructive and Aesthetic Surgery (FEBOPRAS) and member of BAPRAS. She is a female surgeon with more than 20 years of experience, seeing patients at 64 Harley Street, London.
What are the opening hours of the Harley Street clinic for dermal fillers consultations?
The ADLSynergy practice at 64 Harley Street is open every day, Monday to Sunday, from 9:00am to 6:30pm. All dermal fillers consultations are by appointment, so please book ahead by phone, WhatsApp, email or the online contact form.
How do I book a dermal fillers consultation on Harley Street?
Call +44 (0) 7732 475 751, message the team on WhatsApp, email info@adlsynergy.co.uk or use the contact form at adlsynergy.co.uk/contact.html. A member of the team will reply within 24 hours to arrange your dermal fillers consultation with Ms Anna De Leo at 64 Harley Street, London W1G 7HB.
Can I book a dermal fillers appointment at the weekend in London?
Yes. Unlike many Harley Street clinics, the ADLSynergy practice is open seven days a week, including Saturday and Sunday, from 9:00am to 6:30pm. Weekend dermal fillers consultations are by appointment — call +44 (0) 7732 475 751 or send a WhatsApp message to check availability.
Do I need a GP referral for dermal fillers on Harley Street?
No referral is needed to book a private dermal fillers consultation with Ms Anna De Leo at 64 Harley Street. If you plan to claim through private medical insurance, check with your insurer, as some ask for a GP referral first. Bringing a GP letter or any previous reports is always helpful.
What anaesthetic is used for dermal fillers on Harley Street?
Typical anaesthetic for dermal fillers: Topical or local. Ms Anna De Leo confirms the safest option for you at your consultation at 64 Harley Street, London, after reviewing your health and goals.
How soon can I return to work after dermal fillers?
Typical time back to desk-based work after dermal fillers: Usually the same or next day. Everyone heals differently, so Ms Anna De Leo gives you a personalised recovery timeline at your consultation at 64 Harley Street, London, and follows you up throughout.
What should I bring to my dermal fillers consultation in London?
Please bring photo ID, a list of your medications and allergies, details of any previous surgery, relevant scans or reports, and the questions you would like to ask. Ms Anna De Leo will take a full history at her Harley Street practice before recommending any dermal fillers plan.
How do I get to the dermal fillers clinic at 64 Harley Street?
64 Harley Street is a short walk from Regent's Park, Oxford Circus, Bond Street, Great Portland Street and Baker Street Underground stations, and from Marylebone mainline station. Directions and a map are on the Harley Street practice page at adlsynergy.co.uk.
Why choose Harley Street for dermal fillers?
Harley Street has been the centre of British consultative medicine since the 19th century, with specialist doctors concentrated in one Marylebone address. At 64 Harley Street, Ms Anna De Leo combines that tradition with a personalised, female-led approach to dermal fillers and coordinated recovery support.
Does ADLSynergy offer recovery support after dermal fillers?
Yes. After dermal fillers, the ADLSynergy team on Harley Street offers scar therapy, lymphatic care, oxygen and red light therapy, nutrition and breathwork support, all coordinated with Ms Anna De Leo's surgical plan to help you recover well.
Is my dermal fillers consultation confidential?
Completely. Consultations take place privately at 64 Harley Street in a calm, discreet setting, and your personal and medical information is handled confidentially in line with UK GDPR. You can also ask initial questions about dermal fillers by WhatsApp before booking.
Can I see Ms Anna De Leo about dermal fillers outside London?
Ms Anna De Leo's main practice is at 64 Harley Street, London W1G 7HB, open every day, Monday to Sunday, from 9:00am to 6:30pm. She also sees patients in Rome and Palermo, Italy, by appointment — contact the team on +44 (0) 7732 475 751 to arrange a dermal fillers consultation.
How long should I wait between my dermal fillers consultation and surgery?
In line with GMC guidance, there is a cooling-off period of at least two weeks between your consultation and any cosmetic procedure. Ms Anna De Leo encourages a second consultation at 64 Harley Street so you can decide on dermal fillers without any pressure.
64 Harley Street · London W1G

Discuss Dermal Fillers
with Ms Anna De Leo

Every transformation starts with a conversation. Book a private consultation at our Harley Street practice — open every day, by appointment.

This guide is for general information and does not replace a personal medical consultation. All surgery carries risks; results vary from person to person.

Chat with us